Medicina Regenerativa e as Células-tronco
Vimos anteriormente o que são células-tronco, mas para que elas servem?
Neste vídeo vamos ver alguns usos das células-tronco na medicina regenerativa, incluindo os primeiros transplantes de medula óssea e a engenharia de tecidos.
Confira as referências utilizadas e se informe mais sobre o assunto :)
Introduction to Biotechnology, 3rd edition - William J. Thieman, Michael A. Palladino.
Bone marrow transplant. In MedlinePlus, U.S. National Library of Medicine, National Institutes of Health, 2015. http://ow.ly/TBv8N
Egon Lorenz, Charles Congdon, and Delta Uphoff. Modification of Acute Irradiation Injury in Mice and Guinea-Pigs by Bone Marrow Injections. Radiology 58:6, 863-877, 1952. http://dx.doi.org/10.1148/58.6.863
History of Transplantation. Fred Hutchinson Cancer Research Center. http://ow.ly/TBvj5
Bone Marrow (Hematopoietic) Stem Cells. In Stem Cell Information. Bethesda, MD: National Institutes of Health, U.S. Department of Health and Human Services, 2011. http://ow.ly/TBvGa
Noseda et al. PDGFRα demarcates the cardiogenic clonogenic Sca1+ stem/progenitor cell in adult murine myocardium. Nature Communications 6, 2015. http://dx.doi.org/10.1038/ncomms7930
Masumoto et al. Human iPS cell-engineered cardiac tissue sheets with cardiomyocytes and vascular cells for cardiac regeneration. Scientific Reports 4, 2014. http://dx.doi.org/10.1038/srep06716