Humanos Mutantes com Superpoderes

Referências: Boyden et al. High bone density due to a mutation in LDL-receptor–related protein 5. N Engl J Med, 2002; 346:1513-21. https://doi.org/10.1056/NEJMoa013444

Chen et al. Transcriptional regulator PRDM12 is essential for human pain perception. Nature Genetics, 2015; 47:803-8. https://doi.org/10.1038/ng.3308

Yang N, et al. ACTN3 Genotype Is Associated with Human Elite Athletic Performance. Am J Hum Genet. 2003; 73(3): 627–631. https://dx.doi.org/10.1086%2F377590

Roth, SM, et al. The ACTN3 R577X nonsense allele is under-represented in elite-level strength athletes. Eur J Hum Genet. 2008; 16(3): 391–394. https://dx.doi.org/10.1038%2Fsj.ejhg.5201964

Zhao et al. Molecular characterization of loss-of-function mutations in PCSK9 and identification of a compound heterozygote. Am J Hum Genet, 2006; 79(3):514-23. https://doi.org/10.1086/507488

He et al. The transcriptional repressor DEC2 regulates sleep length in mammals. Science, 2009; 325(5942):866-70. https://doi.org/10.1126/science.1174443

June C, Levine B. Blocking HIV’s attack. Scientific American, 2012; 306:54-9. https://doi.org/10.1038/scientificamerican0312-54

McKusick VA. The defect in Marfan syndrome. Nature. 1991; 352: 279-81. https://doi.org/10.1038/352279a0

Wagner KR, Cohen JS. Myostatin-Related Muscle Hypertrophy. 2005 Oct 5 [Updated 2013 Jul 3]. In: Pagon RA, Adam MP, Ardinger HH, et al., editors. GeneReviews® [Internet]. Seattle (WA): University of Washington, Seattle; 1993-2017. Available from: https://www.ncbi.nlm.nih.gov/books/NBK1498/

De la Chapelle A, Träskelin AL, Juvonen E. Truncated erythropoietin receptor causes dominantly inherited benign human erythrocytosis. Proc Natl Acad Sci U S A. 1993; 90(10): 4495–4499. http://bit.ly/2vPFIle

Racimo F, et al. Archaic Adaptive Introgression in TBX15/WARS2. Mol Biol Evol. 2017; 34(3):509-524. http://doi.org/10.1093/molbev/msw283