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Devemos modificar o genoma de embriões?

Com a possibilidade do uso do CRISPR/Cas9, entre outras ferramentas de edição de genes, surgem também questões éticas quanto à modificação do genoma humano. Será que deveríamos modificar o genoma de embriões?

Referências:

Iaccarino M. Science and ethics. EMBO Rep. 2001. 2(9):747-50. http://dx.doi.org/10.1093/embo-reports/kve191

National Academies of Sciences, Engineering, and Medicine. International Summit on Human Gene Editing: A Global Discussion. Washington, DC: The National Academies Press, 2016. http://dx.doi.org/10.17226/21913.

Sivapatham R. Ethical implications of human genetic engineering.

Science of Age – The Buck institute for Research on Aging. 2015. http://bit.ly/2bE860i

Collins FS. Statement on NIH funding of research using gene-editing technologies in human embryos. U.S. Department of Health & Human Services, National Institutes of Health. 2015. http://bit.ly/2bE9m3C

Liang, P., Xu, Y., Zhang, X. et al. Protein Cell (2015) 6: 363. doi:10.1007/s13238-015-0153-5


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